- Research Labs
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20,000 square feetFifty-eight 10 and 8 foot fume hoodsSeparate analytical labsDedicated hydrogenation bayDesigned for synthetic chemistry
- NMR
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300 MHz Bruker400 MHz BrukerMulti-nuclear probeVariable TemperatureUser Walk-up
- Mass Spectroscopy
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Walk-up LC/MS spectrometersGC/MS system
- Purification
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CombiFlash Rf systemsPreparative HPLC systemsAgilent 1100 HPLC units
- Process Equipment
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50L, 22L and 10L ReactorsCooling to -78CDedicated SuiteContainment for high potency
- Additional Analytical
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Walk-up LC/MS spectrometersFT/IRPolarimeter
We don’t just make molecules, we make the right ones. Medicinal chemists are the scientific artists who create new chemical entities. They have the ability to integrate multiple data sources such as synthetic methodology, toxicology, ADME, pharmacology, physico-chemical characteristics and deliver potential new drugs. We are a company of experienced medicinal chemists with each having an average of 15 years of drug discovery and development experience. We provide IP enabling medicinal chemistry expertise, problem solving skills & excellent communication.
Kalexsyn has become known in the industry for its ability to execute challenging syntheses including Class II, III, IV and V compounds.. Much of our custom synthesis work comes from clients who have used other CROs that have failed to deliver a synthetic target. Our success is due to our chemists' decades of experience. At Kalexsyn, we have experience in a broad array of chemistries, allowing us to take on your most challenging targets. We understand the impact of meeting timelines. We have a complete array of analytical equipment at Kalexsyn and all materials are fully characterized prior to shipping. Analytical data packages accompany all shipments.
With advances in mass spectrometry we’ve seen an increase in the requests for preparation of stable label compounds. Our chemists are experienced in the preparation of stable label compounds containing 2H, 13C, 15N, and/or 18O. We can help to support your pre-clinical and clinical development.
Kalexsyn's process improvement and scale-up capabilities can typically prepare 50-500 gram of your target in our early API reaction suite. Our process improvement ideas are discussed with our clients and clear, concise timelines and goals are set.